Your average 10 ounce can of HFC-134a-based (1,1,1,2-Tetrafluoroethane on a MSDS) computer duster has a global warming potential of 405 kg of CO2 equivalent.
In my car, a 2016 Toyota Prius, I could drive about 2380 miles on that amount of tailpipe CO2.
Now, a lot of newer dusters in the US are HFC-152a (1,1-Difluoroethane) instead, and that has a GWP of 124 - so the same 283 gram can has about 35.1 kg CO2 equivalent emissions, equivalent to the tailpipe emissions of about 206 miles of driving in my Prius.
Better, but really, still not good for blowing dust off of stuff.
(Also, the CO2 numbers for the Prius are based on the 170 g/mi figure that the US EPA uses, not (very optimistic) European numbers.)