So, the fact that my main e-mail client (Mailpile) and my social media (Mastodon) are both browser-based means that I cannot easily open random links coming my way through these channels in a separate cube, using porcupine: https://micahflee.com/2016/06/qubes-tip-opening-links-in-your-preferred-appvm/
This is less than ideal. Why does everything have to be browser-based these days.
@rysiek Everything isn't browser-based. There's just a lot of browser-based stuff. I largely ignore it. There are still plenty of non-browser-based mail clients.
There are also lots of desktop clients for Mastodon.
@freakazoid @rysiek and not all of them are just electron wrappers!
@rysiek Then there are Whalebird https://whalebird.org TheDesk https://thedesk.top/en/and Mstdn https://github.com/rhysd/Mstdn
@Ca_Gi @rysiek another gtl client: https://github.com/bleakgrey/tootle
@Ca_Gi Electron, Electron, and a webview-based thing. I only have 16GiB of RAM, can't afford to run that many Electron apps.
@mmn yeah, I might get back to XMPP, but I still feel it needs to make up its mind about a set of baseline extensions that would be expected to be implemented by any compliant server and client. Currently the support matrix is a mess.
IRC -- yes, that's the next thing I am setting up. :)
@rysiek @mmn After you've set up IRC, set up #Bitlbee as a gateway to your instant messenger accounts. There's also a Bitlbee plugin for #Mastodon: https://wiki.bitlbee.org/HowtoMastodon
Server run by the main developers of the project 
It is not focused on any particular niche interest - everyone is welcome as long as you follow our code of conduct!
@rysiek Thunderbird? And I personally wouldn't treat my Mastodon VM as pretty sensitive..