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Mastodon: AboutGet the appKeyboard shortcutsView source codev4.4.0-nightly.2025-04-15

#h3n2

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DoomsdaysCW

Veterinarian Warns of Flu Symptoms in Dogs Pet Parents Should Never Ignore

Dr. Mark discusses dog flu symptoms, prevention, and treatment—and what you should know about the #BirdFlu.

by Nataliya Vaitkevich, Canva
Feb 22, 2025 8:05 AM EST

"With all the recent stories about the outbreaks of #AvianFlu among #cats, we are often asked about how prone our dogs are to this new variant.

"It is not impossible for a dog to catch bird flu, but it is extremely unlikely. The dog flu that was first identified in Chicago in the US is caused by the #H3N2 variant, but the avian flu that has caused the cases in cats after eating raw food or drinking raw milk is caused by a different variant, #H5N1.

"The only H5N1 cases that have been identified in dogs involved direct contact. One was in #Thailand and was probably spread to the dog after eating an infected #duck, and the other was in Canada, where the dog only got sick after eating an infected wild #goose. No cases have been reported after eating raw dog food.

"The other causes of flu in dogs are much more common than the H5N1 variant, and a vaccine for those types has already been developed. Canine flu (#CIV) is caused by H3N8 or H3N2, unlike the H5N1 strain that is making eggs so expensive."

pethelpful.com/dogs/veterinari
#HPAINews #BirdFlu #AvianInfluenza #PetHealth

Public
Giuseppe Michieli

2018-2019 #human seasonal #H3N2 #influenza A virus #spillovers into #swine with demonstrated virus #transmission in #pigs were not sustained in the pig population

Source: Journal of Virology, ABSTRACTHuman seasonal H3 clade 3C3a influenza A viruses (IAV) were detected four times in U.S. pigs from commercial swine farms in Michigan, Illinois, and Virginia in 2019. To evaluate the relative risk of this spillover to the pig population, whole genome sequencing and…

etidioh.wordpress.com/2024/11/

ETIDIoH · 2018-2019 #human seasonal #H3N2 #influenza A virus #spillovers into #swine with demonstrated virus #transmission in #pigs were not sustained in the pig population
More from ETIDIoH
Public
Giuseppe Michieli

#Safety and #immunogenicity of #mRNA-based seasonal #influenza #vaccines formulated to include multiple #H3N2 strains with or without the B/Yamagata strain in #US adults aged 50–75 years: a phase 1/2, open-label, randomised trial, Lancet Infect Dis.: thelancet.com/journals/laninf/

These data support the continued clinical development of mRNA-based next-generation seasonal influenza vaccines with broadened influenza A/H3N2 strain coverage.

Public
Giuseppe Michieli

Fc-dependent protective #efficacy of non-inhibitory #antibodies targeting #influenza A virus #neuraminidase is limited by epitope availability, BioRxIV: biorxiv.org/content/10.1101/20

We aimed to isolate Abs with cross-subtype reactivity vs human #H1N1 & #H3N2 IAVs from transgenic #mice bearing genes encoding human Ig variable regions. We immunized these mice with recombinant N1 & N2 NA proteins, presenting them either as unconjugated soluble proteins or conjugated protein nanoparticles.

Public
Giuseppe Michieli

Whole- #genome #analysis of circulating #influenza A virus (#H3N2) strains in #Shanghai, #China from 2005 to 2023 pubmed.ncbi.nlm.nih.gov/391936

These results indicated that instead of antigenicity differences enabling #evasion of pre-existing #immunity, higher replicative capability more likely contributed to 2a.3a.1 viruses achieving dominance in China.

PubMedWhole-genome analysis of circulating influenza A virus (H3N2) strains in Shanghai, China from 2005 to 2023 - PubMedSeasonal influenza A virus subtype H3N2 (A/H3N2) circulates globally and has been linked to higher hospitalization rates and summer outbreaks in temperate regions. Here, A/H3N2 circulation in Shanghai, China was systematically studied using data and materials generated by the Shanghai influenza surv …
Public
Giuseppe Michieli

#Sequence-based #detection of emerging antigenically novel #influenza A viruses, Proc Roy Soc B.: royalsocietypublishing.org/doi

Detection of evolutionary #transitions in influenza A #H3N2 viruses’ antigenicity is a major obstacle to effective #vaccine design & development. In this study, we describe Novel Influenza Virus A Detector (NIAViD), an unsupervised machine learning tool, adept at identifying these transitions, using the HA1 sequence and associated physico-chemical properties.

Public
Giuseppe Michieli

#Molecular #epidemiology & #phylogenetic analysis of #influenza viruses #H3N2 & B/Victoria during #COVID19 #pandemic in #Guangdong, #China pubmed.ncbi.nlm.nih.gov/390906

Despite the extraordinarily low detection rate of influenza infection, concealed influenza #transmission may occur between individuals during strict COVID-19 control. This ultimately leads to the #accumulation of viral #mutations and accelerated #evolution of H3N2 and B/Victoria viruses.

PubMedMolecular epidemiology and phylogenetic analysis of influenza viruses A (H3N2) and B/Victoria during the COVID-19 pandemic in Guangdong, China - PubMedDespite the extraordinarily low detection rate of influenza infection, concealed influenza transmission may occur between individuals during strict COVID-19 control. This ultimately leads to the accumulation of viral mutations and accelerated evolution of H3N2 and B/Victoria viruses. Monitoring the …
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