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➑️ Content Warning: ⬅️

I am a walking-talking infohazard and am probably dangerous to your wellbeing. I vacillates between curiosity/playfulness, but even IRL I have trouble with signaling intent.

Subverting the way we model the world can break walls we build to protect ourselves. Breaking my own walls is how I overcome my own fears.

This may enhance triggers in those who have differing fear/disgust responses.

Knowing your emotional limits is not a weakness.

I won't be mad if you unfollow.

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Things I've been absolutely fascinated with: and , , , systems and mechanism / , anything, organizational , theory, , , , theory, , , and , risk reward processing, and the nature of in living systems.

Basically I wanna put sentient robotic ants on mars.

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I'm a computer obsessed autistic nerd w/ executive function disorder. I am effectively agoraphobic. I'm so fucked with anxiety/depression/sensory issues that I can't even manage to get on disability.

I'm living on a donation of $100 a month, and by grace of some girl I met on the internet.

I spend most of my time reading science pubs in quest to fix myself, hundreds a day. I have an operating model of disease that lets me make predictions that end up panning out months+years later.

What do?

I'm not a big fan of the business model behind Wolfram's language, but from a design and engineering perspective, it's interactive notebook system is I think, at a fundamental level, one of the most powerful programming constructs I have ever seen.

The idea of being able to puppet Unity from inside of a Wolfram notebook blew my mind.

The stream is over now, and it seems they have a lot more work to do but this is super exciting to see.

Replay :
twitch.tv/stephen_wolfram/v/33

Watching Stephen Wolfram go over their implementation of wolflang inside of unity. Live on twitch twitch.tv/stephen_wolfram

Am reminded of @shanecelis' emacs-like implementation of an interactive console.
m.youtube.com/watch?v=DsqYBiZP

Updated list of #ActivityPub projects in development and/or ready to use:

Twitter -> #Mastodon and #Pleroma

DropBox/Google Drive -> @nextcloud

YouTube -> #PeerTube ( @Chocobozzz )

Instagram -> @pixelfed and @anfora

GrooveShark -> @funkwhale

MeetUp -> @GetTogetherComm

Medium -> #Plume ( @BaptisteGelez ) and @write_as

Reddit -> @prismo and Anancus ( @tuxether )

Google Calendar -> @calendar_social

Feedly -> #ReadAs ( @write_as )

500px -> @peerpx

#Fediverse #federation

"Its story starts with the Latin term Libra Pondo, meaning β€œpound in weight.” This was abbreviated to lb, which we still use. When lb became standard, it was often drawn with a little bar across the tops of both letters (β„”), just to show that the l and the b were connected. As scribes started writing this sign faster and faster, lb began to morph."
99percentinvisible.org/episode (h/t the guy who originally suggested using # as the symbol for birdsite hashtags)

@peter This, basically.

If you judge federated or peer networks by centralised standards, they will never appear successful. If, however, such networks adopt Silicon Valley’s success criteria, they will, by definition, be doomed to fail by becoming what they seek to replace if they β€œsucceed”.

Language delay and poorer school performance in children of mothers with inadequate iodine intake in pregnancy: results from follow-up at 8Β years in the Norwegian Mother and Child Cohort Study link.springer.com/article/10.1 Paper: sci-hub.tw/10.1007/s00394-018-

Watching that Robin Williams Sesame skit from earlier in this thread and I am left wondering if there is an animal that never poops, but eats, breaths, and grows.

I realized one of my goals in life could be succinctly described as "Xanadu, but for web video".

Every-time I renew wovensoup.com for another month of hosting service I find that desire growing.

Last weekend I meme'd my friend into setting up a webcam -> p2p torrent system by hacking against nile.js and I basically read thru all of webtorrent's code to fix a bug we were running into.

Had some major latency issues, but I think it could be improved quite a bit.

Are the tools you're using working for you? What needs to change?

Before you start your day, try to make a list of the 3 most important things to focus on that day.

Bad idea of the day:

Growing coffee beans (a kind of cherry) near bear habitats and harvesting the seeds from their poop. Making a novel version of "civiet coffee" but without the whole animal cruelty thing.

The other interesting thing with bee venom is that is might be helping with a number of auto-immune related disorders like arthritis.

That autoimmune issues in the mom is associated with risk of having autistic kids is fascinating to me because so many of my friends growing up had mothers with immune issues.

It can't be coincidence.

I'm also interested in the whole "bears eating honey" thing and curious how much of a role getting stung impacts their own inflammation factors.

Its a myth that bears like honey, apparently what they eat are the protein rich grubs. I touched a bit on that here: mastodon.social/@ultimape/1008

Interestingly Wikipedia says Spironolactone helps with common issues associated autism/schizophrenia genes. (heart, liver, kidney) so it is very interesting. It seems to have improve heart failure outcomes nejm.org/doi/full/10.1056/NEJM and I'm trying to figure out why.

My best guess is that its inflammation related, but haven't figured out a direct causal chain. But bee venom seems to be the closest in terms of action on the same pathways even down to help with diabetes.

For people doing F->M transitions there is a higher rate of heart disease issues because of underlying factors associated with calcium pathways and effects on the heart.

I'm hoping that I might be able to find a solution for that as so much of my research around the microbiome and my own etiology is around liver/calcium channels and the way cholesterol is affected by testosterone/calcium binding.

Scary stuff to think about, but important to know.
ncbi.nlm.nih.gov/pmc/articles/

Bee venom is neat

Helps macrophages avoid apoptosis
sciencedirect.com/science/arti

Effectively reduces inflammation factors
sciencedirect.com/science/arti

With direct action on the liver
link.springer.com/article/10.1

And may have knock-on effects on cancer treatments by protective effects on the immune system
sciencedirect.com/science/arti

TL;DR: Bee venom might help ease issues with gender transition?
are.na/block/2152237

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