ultimape 🐜💩 💛 @ultimape@mastodon.social

➡️ Content Warning: ⬅️

I am a walking-talking infohazard and am probably dangerous to your wellbeing. I vacillates between curiosity/playfulness, but even IRL I have trouble with signaling intent.

Subverting the way we model the world can break walls we build to protect ourselves. Breaking my own walls is how I overcome my own fears.

This may enhance triggers in those who have differing fear/disgust responses.

Knowing your emotional limits is not a weakness.

I won't be mad if you unfollow.

Things I've been absolutely fascinated with: #governance and #governancestructures, #socialnetworks, #gametheory, #incentive systems and mechanism / #gamedesign, #decentralized anything, organizational #rituals, #advertising theory, #information #networks, #psychology, #sociobiology, #complexsystems theory, #emergence, #swarmcognition, #groupformation and #autopoiesis, risk reward processing, and the nature of #homeostasis in living systems.

Basically I wanna put sentient robotic ants on mars.

I'm a computer obsessed autistic nerd w/ executive function disorder. I am effectively agoraphobic. I'm so fucked with anxiety/depression/sensory issues that I can't even manage to get on disability.

I'm living on a donation of $100 a month, and by grace of some girl I met on the internet.

I spend most of my time reading science pubs in quest to fix myself, hundreds a day. I have an operating model of disease that lets me make predictions that end up panning out months+years later.

What do?

I'm not a big fan of the business model behind Wolfram's language, but from a design and engineering perspective, it's interactive notebook system is I think, at a fundamental level, one of the most powerful programming constructs I have ever seen.

The idea of being able to puppet Unity from inside of a Wolfram notebook blew my mind.

The stream is over now, and it seems they have a lot more work to do but this is super exciting to see.

Replay :
http://www.twitch.tv/stephen_wolfram/v/335096030?sr=a&t=519s

Watching Stephen Wolfram go over their implementation of wolflang inside of unity. Live on twitch http://www.twitch.tv/stephen_wolfram

Am reminded of @shanecelis' emacs-like implementation of an interactive console.
https://m.youtube.com/watch?v=DsqYBiZPzIc

"Its story starts with the Latin term Libra Pondo, meaning “pound in weight.” This was abbreviated to lb, which we still use. When lb became standard, it was often drawn with a little bar across the tops of both letters (℔), just to show that the l and the b were connected. As scribes started writing this sign faster and faster, lb began to morph."
https://99percentinvisible.org/episode/octothorpe/ (h/t the guy who originally suggested using # as the symbol for birdsite hashtags)

Watching that Robin Williams Sesame skit from earlier in this thread and I am left wondering if there is an animal that never poops, but eats, breaths, and grows.

I forget you exist.

It makes me happy when you remind me.

All my threads are laid bare.

"SHOW THREAD" it said.

Bullshitting until the truth comes out.
https://refactorcamp.org/@ultimape/100162640490053079

I realized one of my goals in life could be succinctly described as "Xanadu, but for web video".

Every-time I renew wovensoup.com for another month of hosting service I find that desire growing.

Last weekend I meme'd my friend into setting up a webcam -> p2p torrent system by hacking against nile.js and I basically read thru all of webtorrent's code to fix a bug we were running into.

Had some major latency issues, but I think it could be improved quite a bit.

Bad idea of the day:

Growing coffee beans (a kind of cherry) near bear habitats and harvesting the seeds from their poop. Making a novel version of "civiet coffee" but without the whole animal cruelty thing.

The other interesting thing with bee venom is that is might be helping with a number of auto-immune related disorders like arthritis.

That autoimmune issues in the mom is associated with risk of having autistic kids is fascinating to me because so many of my friends growing up had mothers with immune issues.

It can't be coincidence.

I'm also interested in the whole "bears eating honey" thing and curious how much of a role getting stung impacts their own inflammation factors.

Its a myth that bears like honey, apparently what they eat are the protein rich grubs. I touched a bit on that here: https://mastodon.social/@ultimape/100856919241656620

Interestingly Wikipedia says Spironolactone helps with common issues associated autism/schizophrenia genes. (heart, liver, kidney) so it is very interesting. It seems to have improve heart failure outcomes https://www.nejm.org/doi/full/10.1056/NEJMoa1313731 and I'm trying to figure out why.

My best guess is that its inflammation related, but haven't figured out a direct causal chain. But bee venom seems to be the closest in terms of action on the same pathways even down to help with diabetes.

For people doing F->M transitions there is a higher rate of heart disease issues because of underlying factors associated with calcium pathways and effects on the heart.

I'm hoping that I might be able to find a solution for that as so much of my research around the microbiome and my own etiology is around liver/calcium channels and the way cholesterol is affected by testosterone/calcium binding.

Scary stuff to think about, but important to know.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836937/

Bee venom is neat

Helps macrophages avoid apoptosis
https://www.sciencedirect.com/science/article/pii/S0161589018308691

Effectively reduces inflammation factors
https://www.sciencedirect.com/science/article/abs/pii/S0006295206006010

With direct action on the liver
https://link.springer.com/article/10.1007/s10495-011-0659-0

And may have knock-on effects on cancer treatments by protective effects on the immune system
https://www.sciencedirect.com/science/article/pii/S0304383517303324

TL;DR: Bee venom might help ease issues with gender transition?
https://are.na/block/2152237