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RedRobotCambridge-based Maxion Therapeutics raises €68.9 million in Series A funding led by General Catalyst to advance its KnotBody pipeline targeting ion channel and GPCR-driven diseases.Maxion Therapeutics, a Cambridge-based biotech firm, has raised €68.9 million in a Series A funding round led by General Catalyst. <a href="https://mastodon.social/tags/biotech" class="mention hashtag" rel="tag">#biotech</a> <a href="https://mastodon.social/tags/drugdevelopment" class="mention hashtag" rel="tag">#drugdevelopment</a> <a href="https://mastodon.social/tags/funding" class="mention hashtag" rel="tag">#funding</a> <a href="https://mastodon.social/tags/GPCR" class="mention hashtag" rel="tag">#GPCR</a> <a href="https://mastodon.social/tags/ionchannels" class="mention hashtag" rel="tag">#ionchannels</a> <a href="https://redrobot.online/2025/03/maxion-therapeutics-secures-e68-million-in-series-a-funding-for-antibody-based-drug-development/" target="_blank" rel="nofollow noopener" translate="no">https://redrobot.online/2025/03/maxion-therapeutics-secures-e68-million-in-series-a-funding-for-antibody-based-drug-development/</a>

Ivan Maslov"Direct effect of membrane environment on the activation of mGluR2 revealed by single-molecule FRET" in <a href="https://mstdn.science/tags/Structure" class="mention hashtag" rel="nofollow noopener" target="_blank">#Structure</a>🔗 <a href="https://doi.org/10.1016/j.str.2025.01.011" rel="nofollow noopener" translate="no" target="_blank">https://doi.org/10.1016/j.str.2025.01.011</a>🧵 <a href="https://mstdn.science/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> <a href="https://mstdn.science/tags/mGluR" class="mention hashtag" rel="nofollow noopener" target="_blank">#mGluR</a>🧼<a href="https://mstdn.science/tags/detergents" class="mention hashtag" rel="nofollow noopener" target="_blank">#detergents</a> <a href="https://mstdn.science/tags/cholesterol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cholesterol</a> 🔬 <a href="https://mstdn.science/tags/smFRET" class="mention hashtag" rel="nofollow noopener" target="_blank">#smFRET</a> 💻🧪 <a href="https://mstdn.science/tags/MD" class="mention hashtag" rel="nofollow noopener" target="_blank">#MD</a> <a href="https://mstdn.science/tags/mutants" class="mention hashtag" rel="nofollow noopener" target="_blank">#mutants</a>Congrats to C. Banerjee, B. Liauw, and R. Vafabakhsh!

Emmanuel MargeatCheck our new preprint ! Triple orthogonal labeling with 2 unnatural aminoacids + 1 SNAP-Tag for 3 color <a href="https://mstdn.science/tags/smFRET" class="mention hashtag" rel="nofollow noopener" target="_blank">#smFRET</a>. We resolve a new intermediate in the activation of metabotropic glutamate receptor 2.<a href="https://mstdn.science/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> <a href="https://mstdn.science/tags/clickchemistry" class="mention hashtag" rel="nofollow noopener" target="_blank">#clickchemistry</a><a href="https://biorxiv.org/content/10.1101/2024.10.31.621373v1" rel="nofollow noopener" translate="no" target="_blank">https://biorxiv.org/content/10.1101/2024.10.31.621373v1</a>Collaboration with Jean Philippe Pin & Philippe Rondard (IGF Montpellier) & Don Lamb (LMU Munich)

Science NewsBiophysicists at <a href="https://idw-online.social/tags/UniLeipzig" class="mention hashtag" rel="nofollow noopener" target="_blank">#UniLeipzig</a> demonstrate mechanism of <a href="https://idw-online.social/tags/signalling" class="mention hashtag" rel="nofollow noopener" target="_blank">#signalling</a> by adrenaline-binding <a href="https://idw-online.social/tags/receptor" class="mention hashtag" rel="nofollow noopener" target="_blank">#receptor</a> at atomic level. In the future, researchers could use the results to avoid side effects when developing drugs. <a href="https://idw-online.social/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> @SFB1423<a href="https://nachrichten.idw-online.de/2024/06/21/leipzig-biophysicists-decipher-functionality-of-adrenaline-binding-receptor" rel="nofollow noopener" translate="no" target="_blank">https://nachrichten.idw-online.de/2024/06/21/leipzig-biophysicists-decipher-functionality-of-adrenaline-binding-receptor</a>

idw_onlineBiophysicists at <a href="https://idw-online.social/tags/UniLeipzig" class="mention hashtag" rel="nofollow noopener" target="_blank">#UniLeipzig</a> demonstrate mechanism of <a href="https://idw-online.social/tags/signalling" class="mention hashtag" rel="nofollow noopener" target="_blank">#signalling</a> by adrenaline-binding <a href="https://idw-online.social/tags/receptor" class="mention hashtag" rel="nofollow noopener" target="_blank">#receptor</a> at atomic level. In the future, researchers could use the results to avoid side effects when developing drugs. <a href="https://idw-online.social/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> @SFB1423<a href="https://nachrichten.idw-online.de/2024/06/21/leipzig-biophysicists-decipher-functionality-of-adrenaline-binding-receptor" rel="nofollow noopener" translate="no" target="_blank">https://nachrichten.idw-online.de/2024/06/21/leipzig-biophysicists-decipher-functionality-of-adrenaline-binding-receptor</a>

idw_onlineBiophysiker der <a href="https://idw-online.social/tags/UniLeipzig" class="mention hashtag" rel="nofollow noopener" target="_blank">#UniLeipzig</a> weisen Mechanismus der <a href="https://idw-online.social/tags/Signal%C3%BCbertragung" class="mention hashtag" rel="nofollow noopener" target="_blank">#Signalübertragung</a> durch Adrenalin-bindenden <a href="https://idw-online.social/tags/Rezeptor" class="mention hashtag" rel="nofollow noopener" target="_blank">#Rezeptor</a> auf atomarer Ebene nach. Mit den Ergebnissen könnten Forschende künftig Nebenwirkungen bei <a href="https://idw-online.social/tags/Entwicklung" class="mention hashtag" rel="nofollow noopener" target="_blank">#Entwicklung</a> von Wirkstoffen umgehen. <a href="https://idw-online.social/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> @SFB1423<a href="https://nachrichten.idw-online.de/2024/06/21/leipziger-biophysiker-entschluesseln-funktionsweise-von-adrenalin-bindendem-rezeptor" rel="nofollow noopener" translate="no" target="_blank">https://nachrichten.idw-online.de/2024/06/21/leipziger-biophysiker-entschluesseln-funktionsweise-von-adrenalin-bindendem-rezeptor</a>

Gaspar JekelyThe version of record of our <a href="https://biologists.social/tags/Nematostella" class="mention hashtag" rel="nofollow noopener" target="_blank">#Nematostella</a> <a href="https://biologists.social/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> <a href="https://biologists.social/tags/neuropeptide" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuropeptide</a> paper has now been published <a href="https://elifesciences.org/articles/90674#content" rel="nofollow noopener" translate="no" target="_blank">https://elifesciences.org/articles/90674#content</a>For <a href="https://biologists.social/tags/cnidarian" class="mention hashtag" rel="nofollow noopener" target="_blank">#cnidarian</a> <a href="https://biologists.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuroscience</a> there are lots of new deorphanised receptors described in the paper. We also identified orthologs across cnidarian species, including corals, <a href="https://biologists.social/tags/Exaiptasia" class="mention hashtag" rel="nofollow noopener" target="_blank">#Exaiptasia</a> etc. so the resource is not limited to Nematostella.

PLOS BiologyNew study shows that the C-terminal fragment of the <a href="https://fediscience.org/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> <a href="https://fediscience.org/tags/muscarinicM2receptor" class="mention hashtag" rel="nofollow noopener" target="_blank">#muscarinicM2receptor</a>, translated from an <a href="https://fediscience.org/tags/IRES" class="mention hashtag" rel="nofollow noopener" target="_blank">#IRES</a>, localizes to the <a href="https://fediscience.org/tags/mitochondrial" class="mention hashtag" rel="nofollow noopener" target="_blank">#mitochondrial</a> inner membrane & is upregulated upon stress exposure, reducing respiration & <a href="https://fediscience.org/tags/ROS" class="mention hashtag" rel="nofollow noopener" target="_blank">#ROS</a> to protect cells <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/3Uomtb8" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3Uomtb8</a>

Gaspar JekelyFor our <a href="https://biologists.social/tags/Nematostella" class="mention hashtag" rel="nofollow noopener" target="_blank">#Nematostella</a> neuropeptide-GPCR screen paper <a href="https://elifesciences.org/reviewed-preprints/90674v1" rel="nofollow noopener" translate="no" target="_blank">https://elifesciences.org/reviewed-preprints/90674v1</a>, we have now published a detailed protocol here: <a href="https://www.bio-protocol.org/exchange/preprintdetail?type=3&id=2493" rel="nofollow noopener" translate="no" target="_blank">https://www.bio-protocol.org/exchange/preprintdetail?type=3&id=2493</a> If you are interested in <a href="https://biologists.social/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> <a href="https://biologists.social/tags/neuropeptide" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuropeptide</a> <a href="https://biologists.social/tags/pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#pharmacology</a> <a href="https://biologists.social/tags/cnidaria" class="mention hashtag" rel="nofollow noopener" target="_blank">#cnidaria</a> <a href="https://biologists.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuroscience</a> have a look!

nemo™ 🇺🇦<a href="https://mas.to/tags/BC007" class="mention hashtag" rel="nofollow noopener" target="_blank">#BC007</a> ist ein potenzieller Wirkstoffkandidat gegen das <a href="https://mas.to/tags/PostCovidSyndrom" class="mention hashtag" rel="nofollow noopener" target="_blank">#PostCovidSyndrom</a> und andere <a href="https://mas.to/tags/Autoimmunkrankheiten" class="mention hashtag" rel="nofollow noopener" target="_blank">#Autoimmunkrankheiten</a> mit funktionellen Autoantikörpern gegen <a href="https://mas.to/tags/GProtein" class="mention hashtag" rel="nofollow noopener" target="_blank">#GProtein</a> gekoppelte Rezeptoren <a href="https://mas.to/tags/gpcr" class="mention hashtag" rel="nofollow noopener" target="_blank">#gpcr</a> Es handelt sich um ein <a href="https://mas.to/tags/aptamer" class="mention hashtag" rel="nofollow noopener" target="_blank">#aptamer</a> das diese krankmachenden <a href="https://mas.to/tags/Autoantik%C3%B6rper" class="mention hashtag" rel="nofollow noopener" target="_blank">#Autoantikörper</a> blockieren soll. Die klinische Phase-II-Studie reCOVer der Augenklinik des <a href="https://mas.to/tags/Uniklinikums" class="mention hashtag" rel="nofollow noopener" target="_blank">#Uniklinikums</a> <a href="https://mas.to/tags/Erlangen" class="mention hashtag" rel="nofollow noopener" target="_blank">#Erlangen</a> untersucht den molekularen Weg bestimmter Autoantikörper beim Post-COVID-Syndrom. In diesem Zusammenhang startet in …(1/2)

J.H.NoyesLonghaulers should petition for access to this molecule. It will help. Very interesting the way it works. Both sources describe it better than I could myself, so I'll just point you in their direction.Popular: <a href="http://www.dicyt.com/viewNews.php?newsId=32527" rel="nofollow noopener" translate="no" target="_blank">http://www.dicyt.com/viewNews.php?newsId=32527</a>In depth: <a href="https://www.researchgate.net/publication/268197277_Targeting_the_minor_pocket_of_C5aR_for_the_rational_design_of_an_oral_allosteric_inhibitor_for_inflammatory_and_neuropathic_pain_relief" rel="nofollow noopener" translate="no" target="_blank">https://www.researchgate.net/publication/268197277_Targeting_the_minor_pocket_of_C5aR_for_the_rational_design_of_an_oral_allosteric_inhibitor_for_inflammatory_and_neuropathic_pain_relief</a><a href="https://mastodon.online/tags/LongCovid" class="mention hashtag" rel="nofollow noopener" target="_blank">#LongCovid</a> <a href="https://mastodon.online/tags/C5a" class="mention hashtag" rel="nofollow noopener" target="_blank">#C5a</a> <a href="https://mastodon.online/tags/C5aInhibitor" class="mention hashtag" rel="nofollow noopener" target="_blank">#C5aInhibitor</a> <a href="https://mastodon.online/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> <a href="https://mastodon.online/tags/Covid" class="mention hashtag" rel="nofollow noopener" target="_blank">#Covid</a>

PLOS BiologyThe <a href="https://fediscience.org/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> CMKLR1 responds to the <a href="https://fediscience.org/tags/adipokine" class="mention hashtag" rel="nofollow noopener" target="_blank">#adipokine</a> <a href="https://fediscience.org/tags/chemerin" class="mention hashtag" rel="nofollow noopener" target="_blank">#chemerin</a> and is abundant in <a href="https://fediscience.org/tags/InnateImmune" class="mention hashtag" rel="nofollow noopener" target="_blank">#InnateImmune</a> cells. Structure of CMKLR1 in complex with <a href="https://fediscience.org/tags/Gprotein" class="mention hashtag" rel="nofollow noopener" target="_blank">#Gprotein</a> and a peptide agonist (+ mutagenesis & simulations) reveals mechanisms of action <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/4a6Igvd" rel="nofollow noopener" target="_blank">https://plos.io/4a6Igvd</a>

RCNS MedChem Research GroupGproteinDb update brings new G protein- <a href="https://mastodon.social/tags/GPCR" class="mention hashtag" rel="tag">#GPCR</a> couplings, AlphaFold2-multimer models, interface interactions and coupling selectivity analysis <a href="https://t.co/goZcFihoeX" target="_blank" rel="nofollow noopener" translate="no">https://t.co/goZcFihoeX</a>

CellBioNewsResearch reveals molecular mechanism of asymmetric <a href="https://scientificnetwork.de/tags/calcium_sensitive" class="mention hashtag" rel="nofollow noopener" target="_blank">#calcium_sensitive</a> <a href="https://scientificnetwork.de/tags/receptor" class="mention hashtag" rel="nofollow noopener" target="_blank">#receptor</a> activation.<a href="https://scientificnetwork.de/tags/CaSR" class="mention hashtag" rel="nofollow noopener" target="_blank">#CaSR</a> <a href="https://scientificnetwork.de/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a><a href="https://phys.org/news/2023-11-reveals-molecular-mechanism-asymmetric-calcium-sensitive.html" rel="nofollow noopener" translate="no" target="_blank">https://phys.org/news/2023-11-reveals-molecular-mechanism-asymmetric-calcium-sensitive.html</a>

Cell Chemical BiologyThe November Issue of @CellChemBiol is Online! Read it at: <a href="https://www.cell.com/cell-chemical-biology/current?utm_source=dlvr.it&utm_medium=mastodon" rel="nofollow noopener" translate="no" target="_blank">https://www.cell.com/cell-chemical-biology/current?utm_source=dlvr.it&utm_medium=mastodon</a> <a href="https://mstdn.science/tags/chemicalbiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#chemicalbiology</a> <a href="https://mstdn.science/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> <a href="https://mstdn.science/tags/RAF" class="mention hashtag" rel="nofollow noopener" target="_blank">#RAF</a> <a href="https://mstdn.science/tags/STING" class="mention hashtag" rel="nofollow noopener" target="_blank">#STING</a> <a href="https://mstdn.science/tags/SARSCOV2" class="mention hashtag" rel="nofollow noopener" target="_blank">#SARSCOV2</a> <a href="https://mstdn.science/tags/ASO" class="mention hashtag" rel="nofollow noopener" target="_blank">#ASO</a> <a href="https://mstdn.science/tags/PDL1" class="mention hashtag" rel="nofollow noopener" target="_blank">#PDL1</a> <a href="https://mstdn.science/tags/HDAC" class="mention hashtag" rel="nofollow noopener" target="_blank">#HDAC</a> <a href="https://mstdn.science/tags/indoxylsulfate" class="mention hashtag" rel="nofollow noopener" target="_blank">#indoxylsulfate</a> <a href="https://mstdn.science/tags/E3ligase" class="mention hashtag" rel="nofollow noopener" target="_blank">#E3ligase</a> <a href="https://mstdn.science/tags/UPS10" class="mention hashtag" rel="nofollow noopener" target="_blank">#UPS10</a> <a href="https://mstdn.science/tags/targetID" class="mention hashtag" rel="nofollow noopener" target="_blank">#targetID</a> <a href="https://mstdn.science/tags/luciferin" class="mention hashtag" rel="nofollow noopener" target="_blank">#luciferin</a> <a href="https://mstdn.science/tags/forwardgenetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#forwardgenetics</a>

CellBioNews<a href="https://scientificnetwork.de/tags/Glucagon" class="mention hashtag" rel="nofollow noopener" target="_blank">#Glucagon</a> <a href="https://scientificnetwork.de/tags/receptor" class="mention hashtag" rel="nofollow noopener" target="_blank">#receptor</a> structures uncover new <a href="https://scientificnetwork.de/tags/arrestin" class="mention hashtag" rel="nofollow noopener" target="_blank">#arrestin</a> interaction mechanism.<a href="https://scientificnetwork.de/tags/signalling" class="mention hashtag" rel="nofollow noopener" target="_blank">#signalling</a> <a href="https://scientificnetwork.de/tags/transduction" class="mention hashtag" rel="nofollow noopener" target="_blank">#transduction</a> <a href="https://scientificnetwork.de/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a><a href="https://phys.org/news/2023-08-glucagon-receptor-uncover-arrestin-interaction.html" rel="nofollow noopener" target="_blank">https://phys.org/news/2023-08-glucagon-receptor-uncover-arrestin-interaction.html</a>

Martin VögeleFirst preprint about my work at Schrödinger:We show how to predict ligand efficacy via absolute binding free energy perturbation on different receptor conformations — confirming and utilizing the principle that the functional response of a receptor is mainly determined by the thermodynamics of ligand binding.<a href="https://chemrxiv.org/engage/chemrxiv/article-details/64b1cccaae3d1a7b0db45aa8" rel="nofollow noopener" target="_blank">https://chemrxiv.org/engage/chemrxiv/article-details/64b1cccaae3d1a7b0db45aa8</a><a href="https://fediscience.org/tags/FEP" class="mention hashtag" rel="nofollow noopener" target="_blank">#FEP</a> <a href="https://fediscience.org/tags/FreeEnergy" class="mention hashtag" rel="nofollow noopener" target="_blank">#FreeEnergy</a> <a href="https://fediscience.org/tags/LigandEfficacy" class="mention hashtag" rel="nofollow noopener" target="_blank">#LigandEfficacy</a> <a href="https://fediscience.org/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> <a href="https://fediscience.org/tags/DrugDiscovery" class="mention hashtag" rel="nofollow noopener" target="_blank">#DrugDiscovery</a> <a href="https://fediscience.org/tags/DrugDesign" class="mention hashtag" rel="nofollow noopener" target="_blank">#DrugDesign</a> <a href="https://fediscience.org/tags/Thermodynamics" class="mention hashtag" rel="nofollow noopener" target="_blank">#Thermodynamics</a> <a href="https://fediscience.org/tags/GPCRs" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCRs</a> <a href="https://fediscience.org/tags/BindingFreeEnergy" class="mention hashtag" rel="nofollow noopener" target="_blank">#BindingFreeEnergy</a>

Gaspar JekelyOur favourite <a href="https://biologists.social/tags/Platynereis" class="mention hashtag" rel="nofollow noopener" target="_blank">#Platynereis</a> <a href="https://biologists.social/tags/opsin" class="mention hashtag" rel="nofollow noopener" target="_blank">#opsin</a> now in the mammalian brain as a new <a href="https://biologists.social/tags/optogenetic" class="mention hashtag" rel="nofollow noopener" target="_blank">#optogenetic</a> tool!"Here we ... found that the Platynereis dumerilii ciliary opsin ... is an efficient, versatile, light-activated bistable GPCR that can suppress synaptic transmission in mammalian neurons with high temporal precision in-vivo "<a href="https://www.biorxiv.org/content/10.1101/2023.07.01.547328v1" rel="nofollow noopener" target="_blank">https://www.biorxiv.org/content/10.1101/2023.07.01.547328v1</a><a href="https://biologists.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuroscience</a> <a href="https://biologists.social/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a>

John F. FoleyIn Editors' Choice in Science Signaling, I highlight a study by Park, Martemyanov, Garcia-Marcos, and colleagues revealing another level of bias in GPCR signaling. In the context of neurotransmission, the authors showed that the protein GINIP bound to GTP-bound Galphai subunits, preventing them from interacting with their effectors. As a result, signaling by Gbetagamma subunits was enhanced, biasing the response to GPCR stimulation. Read my summary here: <a href="https://www.science.org/doi/10.1126/scisignal.adj6131" target="_blank" rel="nofollow noopener" translate="no">https://www.science.org/doi/10.1126/scisignal.adj6131</a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="tag">#science</a> <a href="https://mastodon.social/tags/gpcr" class="mention hashtag" rel="tag">#gpcr</a>

Gaspar JekelyPreviously, only one <a href="https://qoto.org/tags/GPCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#GPCR</a> with a ligand was known in <a href="https://qoto.org/tags/cnidaria" class="mention hashtag" rel="nofollow noopener" target="_blank">#cnidaria</a>, the receptor for the <a href="https://qoto.org/tags/Clytia" class="mention hashtag" rel="nofollow noopener" target="_blank">#Clytia</a> Maturation-Inducing-Hormone. This receptor was found by Gonzalo Quiroga Artigas and Philipp Bauknecht in our lab, in a collaboration with Evelyn Houliston. <a href="https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000614" rel="nofollow noopener" target="_blank">https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000614</a> <a href="https://qoto.org/tags/cnidaria" class="mention hashtag" rel="nofollow noopener" target="_blank">#cnidaria</a> <a href="https://qoto.org/tags/neuropeptide" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuropeptide</a> <a href="https://qoto.org/tags/evolution" class="mention hashtag" rel="nofollow noopener" target="_blank">#evolution</a> <a href="https://qoto.org/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuroscience</a>

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