Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19
Interesting new paper in #nature
PubMedCryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19 - PubMedProgression through the cell cycle is controlled by regulated and abrupt changes in phosphorylation<sup>1</sup>. Mitotic entry is initiated by increased phosphorylation of mitotic proteins, a process driven by kinases<sup>2</sup>, whereas mitotic exit is achieved by counteracting dephosphorylation, …