Century-old #genetics mystery of #Mendel’s #peas finally solved
Researchers pinpoint the #genes responsible for the final three pea traits studied by the famed citizen scientist. https://www.nature.com/articles/d41586-025-01269-8

Century-old #genetics mystery of #Mendel’s #peas finally solved
Researchers pinpoint the #genes responsible for the final three pea traits studied by the famed citizen scientist. https://www.nature.com/articles/d41586-025-01269-8
"Early in development when we are still in the womb, very little about us is “determined.” Indeed, the structures that become our reproductive system start out as multi-potential, capable of taking on many possible forms. A neutral structure called the germinal ridge, for example, can develop into ovaries or testes—the structures that produce reproductive cells and sex hormones—or sometimes into something in between, depending on the molecular signals it receives.
Our #genes influence this process, of course. But so do interactions among cells, molecules in our body, including hormones, and influences from the outside world."
DNA and AI
How are these tools reshaping our understanding of the origins of the human species?
The eukaryotic cell emerged as an evolutionary algorithmic phase transition / Eukaryogenesis happened abruptly, led by the tension of increasing gene length and the constraints on producing longer proteins / Evolvement of the eukaryotic cell is the most significant increase in complexity in the history of life's evolution on Earth https://press.uni-mainz.de/eukaryotic-cell-emerged-as-evolutionary-algorithmic-phase-transition/
Xue et al. won a 2024 #JSE Outstanding Paper Award for thisstudy that used mitochondrial #genes from 18 angiosperms to fill sampling gaps for #phylogenomic inferences of early flowering #plant diversification!
https://jse.ac.cn/EN/10.1111/jse.12708
@WileyEcolEvol
#evolution #systematics
A new study revealed that #caffeine impacts your thinking skills is not just about how much #coffee you drink, but also about your #genes. Researchers discovered people with genes for fast caffeine processing performed differently on cognitive tests depending on their caffeine consumption levels, particularly in tasks involving emotion recognition and complex thinking. Suggests #genetic makeup plays a significant role in how we respond to caffeine’s effects on brainpower.
https://journals.sagepub.com/doi/10.1177/02698811241303601
https://osf.io/preprints/psyarxiv/rehdj_v1 #familytraits #JavaScript #HackerNews #ngated
SciTech Chronicles. . . . . . . . .April 2nd, 2025
Cruciferous #plants' pungent defense mechanism: How repurposed #stomatal #genes also fend off #herbivores.
#evolution #Brassicales #FAMA #myrosin_cells #WASABI_MAKER #SCAP1
https://phys.org/news/2025-03-cruciferous-pungent-defense-mechanism-repurposed.html
“Spare” living human bodies might provide us with organs for transplantation
https://www.technologyreview.com/2025/03/28/1113923/spare-living-human-bodies-might-provide-organs/
Unlocking #rice's yield potential: Trio of #genes holds the key, study shows.
#agriculture #food_security #development #OsMED23, #OsJMJ703 #OsWOX3A #histone_demethylase #transcription_factor
https://phys.org/news/2025-03-rice-yield-potential-trio-genes.html
Heads up. Get your data out of 23andMe right now -- or try.
(Anyone who put it in there in the first place was a fool, I have to say...)
Let's see if the U.S. Government buys it...
https://www.washingtonpost.com/technology/2025/03/24/23andme-dna-privacy-delete/
SciTech Chronicles. . . . . . . . .Mar 24th, 2025
#genes #chromosome #hippocampus #myelin #Aardvark #multimodal #GFS #democratising #cognitive #assessment #Human-AI #Collaboration #E2A #192Tbit/s #Alcatel #2028 #genomics #bioinformatics #antimicrobial
Let students engage in scientific thinking about #genes, #traits, #mutations, and selection agents with Natural Selection. Explore the distribution of bunnies over time and hypothesize about which traits may be favored in different conditions. #Genetics
https://phet.colorado.edu/en/simulations/natural-selection/
My day job is all about #genes, so I applaud the #genomic revolution in #paleontology and #evolutionary #biology. But #evolution really is more than a shift in #allele frequencies over time. It's also change in the #phenotypes those alleles produce, and their #interaction with the world around them.
So I'm equally excited about the #quantitative revolution in describing and cataloguing #traits which until recently could only be analyzed #qualitatively. There's a whole new window opening into the history of life.
**Biological Constraint Engine**
Validates generated sequences against biological feasibility rules
Predicts #protein folding, metabolic interactions, and cellular dynamics
(Again this is something #AI is already good at)
Ensures synthetic organisms would be thermodynamically viable
**Simulation Environment**
Virtual cell environment to test synthetic genomes before physical synthesis.
(We have done this a while ago - pre AI)
Models interactions between #genes, #proteins, and environment
5/6