Hearing begins with the stretching of elastic molecular “springs” that open ion channels in the sensory hair cells of the ear. For decades, researchers have been unable to find these.
Now, a team at Göttingen's Excellence Cluster Multiscale Bioimaging #MBExC has discovered just such a spring for the first time: https://www.uni-goettingen.de/en/3240.html?id=7736
#NatureNeuroscience: https://doi.org/n86s #MakingSenseOfSenses #Hearing
Heute, am 3. März, ist Welttag des Hörens! Doch wie funktioniert eigentlich das #Gehör?
Ein Team des Göttinger Exzellenzclusters „Multiscale Bioimaging“ (#MBExC), an dem auch unsere Uni beteiligt ist, hat dazu eine zentrale Struktur entdeckt. Forschende suchen diese Struktur schon seit über 40 Jahren. Wie die sogenannte „Feder im Ohr“ das #Hören steuert: https://www.uni-goettingen.de/de/3240.html?id=7735
Forschung in #NatureNeuroscience: https://doi.org/10.1038/s41593-024-01849-3
Long-term memory (LTM) does not require the formation of short-term memory (STM), and CaMKII-dependent plasticity specifically regulates STM for avoidance memory. #NatureNeuroscience
www.nature.com/articles/s41...
Formation of long-term memory ...
#NatureNeuroscience Membrane mechanics dictate axonal pearls-on-a-string morphology and function https://www.nature.com/articles/s41593-024-01813-1 #ScienceNews Controversial study redraws classical picture of the neuron in mouse. It suggests “pearling” of axons may help signaling https://www.science.org/content/article/controversial-study-redraws-classical-picture-neuron "Unmyelinated axons of the mouse brain have nonsynaptic, nanoscopic varicosities ~200 nm in diameter repeatedly along their length interspersed with a thin cable ~60 nm in diameter like pearls-on-a-string. This axon nanopearling can be explained by membrane mechanical properties. Neuronal activity modulates plasma membrane cholesterol concentration, leading to changes in axon nanopearls and causing slowing of action potential conduction velocity. Biophysical forces dictate axon morphology and function, and its modulation underlies axonal plasticity."
CONTROVERSIAL STUDY ON SELF-CLEANING BRAINS
Mastodon Post
The British Psychological Society
New sleep study ignites brain cleaning controversy
Recent work challenges ideas of increased toxin clearance during sleep — though some researchers question the study’s methods.
19 June 2024
By Emma Young
https://www.bps.org.uk/research-digest/new-sleep-study-ignites-brain-cleaning-controversy
Credit where credit is due: I learned of this study from NPR. NPR has a good mobile app.
:
#alzheimers #alzheimersdisease #andaweimiao #billwisden #dementiaresearch #dementiaresearchinstitute #glymphatic #glymphaticsystem #glymphaticsystemhypothesis #imperialcollegelondon #maikennedergaard #medicalscience #medicalsciencenews #nationalpublicradio #natureneuroscience #nickfranks #npr #radio #radiomobileapp #radiomobileapps #science #sciencenews #sleepstudies #sleepstudy #toxinclearance #toxinclearanceduringsleep
:::
Sleep does not help brain wash out toxins, study suggests | Neuroscience | The Guardian
https://www.theguardian.com/science/article/2024/may/13/sleep-does-not-help-brain-wash-out-toxins-study-suggests
#Brain
#Toxins
#ClearanceOfFluid
#ImperialCollegeLondon
#Memory
#HandEyeCoordination
#IndirectEvidence
#BrainsWasteRemovalSystem
#NatureNeuroscience
#UKDementiaResearchInstitute
So excited to share chapter 2 of my dissertation, published today in #NatureNeuroscience. We used movie to capture how the brain represents emotion concepts (e.g., angry, sad, happy, etc) in 5-to-15-year-old children. Two main findings:
First, each emotion is represented in a distinct way across the brain.
Second, activation more broadly synchronizes with age, suggesting that we develop a shared interpretation of emotion cues across adolescence. #neuroscience #science
It's been 1 yr since #NatureNeuroscience announced their #OpenAccess fee of €9,500/US $11,390/£8,290 (the choice of listing only those 3 currencies is arbitrary and not necessarily an indicator of where the money will likely come from, right??).
This is, in the words of Dr. Glaucomflecken, academic #journals doing #crime
https://www.youtube.com/watch?v=8F9gzQz1Pms
