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#ocular

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Giuseppe Michieli

#Fatal #Infection in #Ferrets after
#Ocular #Inoculation with Highly Pathogenic Avian #Influenza A(#H5N1), Emerg Infect Dis.: wwwnc.cdc.gov/eid/article/30/7

Ocular inoculation of a clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) virus caused severe and fatal infection in ferrets. Virus was transmitted to ferrets in direct contact. The results highlight the potential capacity of these viruses to cause human disease after either respiratory or ocular exposure.

Emerging Infectious Diseases journalFatal Infection in Ferrets after Ocular Inoculation with Highly Pathogenic Avian Influenza A(H5N1)Fatal Infection in Ferrets after Ocular Inoculation with Highly Pathogenic Avian Influenza A(H5N1) Virus
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hackaday unofficial

Lego Microscope Aims to Discover Future Scientists

When it comes to inspiring a lifelong appreciation of science, few experiences are as powerful as that first glimpse of the world swimming in a drop of pond water as seen through a decent microscope. But sadly, access to a microscope is hardly universal, denying that life-changing view of the world to far too many people.

There have been plenty of attempts to fix this problem before, but we're intrigued to see Legos used to build a usable microscope, primarily for STEM outreach. It's the subject of a scholarly paper (preprint) by [Bart E. Vos], [Emil Betz Blesa], and [Timo Betz]. The build almost exclusively uses Lego parts -- pretty common ones at that -- and there's a complete list of the parts needed, which can either be sourced from online suppliers, who will kit up the parts for you, or by digging through the old Lego bin. Even the illuminator is a stock part, although you'll likely want to replace the orange LED buried within with a white one. The only major non-Lego parts are the lenses, which can either be sourced online or, for the high-power objective, pulled from an old iPhone camera. The really slick part is the build instructions (PDF), which are formatted exactly like the manual from any Lego kit, making the build process easily accessible to anyone who has built Lego before.

As for results, they're really not bad. Images of typical samples, like salt crystal, red onion cells, and water fleas are remarkably clear and detailed. It might no be a lab-grade Lego microscope, but it looks like it's more than up to its intended use.

Thanks for the heads up on this, [Jef].

image
#mischacks#camera#lego
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